According to the wiki this is a common lodging house later known as Wilmotts lodginh house, and linked to the Jack the Ripper case. **
Spitalfields index
A listing of historical public houses, Taverns, Inns, Beer Houses and Hotels in Spitalfields, London.
Residents at this address
1851/Patrick Hurley/Beer shop Keeper/46/Cork/Census
1851/Ann Hurley/Wife/45/Spitalfields/Census
1851/Margaret Hurley/Daughter/18/Spitalfields/Census
1851/John Hurley/Son/13/Spitalfields/Census
1851/Sophia Hurley/Daughter/17/Spitalfields/Census
1856/Patrick Hurley/Beer Retailer/../../Post Office Directory
** Provided By Stephen Harris